Boston University School of Medicine, Biomedical GeneticsSenior Research Assistant
Feb. 2006 - Aug. 2013Boston, Massachusetts, USAActive participation in the study design, execution of laboratory experimental procedures using cutting edge technology and development of protocols to fit the studies’ needs. Experiments included, but were not limited to • genome-wide studies of large number of population samples using microarrays for genotyping, gene expression and copy number variation analysis
• targeted variation and gene studies using Real-Time PCR • genomic studies using Next Generation Sequencing (DNA-Seq, RNA-Seq, Targeted library prep) • in vitro differentiation of human ES/iPS cells to neuronal cells
• utilization of mammalian cell lines, cell based assays, Western blotting and RT-PCR • microfluidic electrophoresis to ensure sample quality and integrity and data reproducibility Projects: • Jan. 2012 – Aug. 2013
iPS-derived neuronal cells as a study model for Alzheimer’s disease
• Apr. 2008 – Aug. 2013
Genetics of Post-Traumatic Stress Disorder and traumatic brain injury (in conjunction with the National Center for PTSD, Behavioral Sciences Division, VA Boston Healthcare System)
• Feb. 2006 – Aug. 2013
Multidisciplinary study of genetic modifiers of sickle cell anemia disease and β-thalassaemia (part of the study being a collaboration with research groups in Brazil and Saudi Arabia)
• Feb. 2006 – Aug. 2013
Genetics of centenarians (partly collaboration with research groups in Italy and Japan)
• Feb. 2006 – Jan. 2010
Genetic background of Alzheimer’s disease