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Work Background
NUS Yong Loo Lin School of MedicineProgram Manager (Admin Lead), Precision Medicine Translational Research Programme
Jan. 2022 - Jan. 2024SingaporeProfessional Achievements:
● Spearheaded the conceptualisation and execution of the programme for the inaugural Precision Medicine Symposium and the first Scientific Advisory Board (SAB) Meeting. ● Managed two strategic precision medicine projects focusing on advanced patient and multi-omics profiling within stringent budgets and timelines. ● Co-developed PM TRP’s microsite with external vendors and Digital Transformation unit boosting digital outreach and organisational branding. ● Enhanced grant management processes, contributing to organisational service excellence under Ron Kaufman’s mentorship. Strategic Programme Development:
● Led the development of budget forecasts and national grant allocation strategies, enhancing PM TRP's core funding framework. Managed grant variations and proposals efficiently, aligning resources with strategic goals.
● TRP's Annual Progress Report and Workplan, highlighting TRP’s KPI, achievements and future directions. These key documents facilitated stakeholder engagement and strategic planning, reflecting an in-depth understanding of organisational objectives.
● Central to drafting and submitting impactful grant proposals, including detailed budgets. Oversaw SAB report processes, ensuring alignment with TRP’s strategic and compliance standards. Operational Excellence and Stakeholder Engagement: ● Overall saw comprehensive research programme operations including objective setting, planning resource allocation, budgeting and hiring. ● Excelled in synthesizing information from diverse stakeholders, applying organisational perspectives to facilitate strategic decisions and alignment across PM TRP.
Duke-NUS Medical SchoolSenior Research Assistant
Nov. 2020 - Aug. 2021Centre for Computational Biology (CCB) Assistant Professor Lisa Tucker-Kellogg's Lab Laboratory for Computational & Cellular Modelling • Lab Management, lab safety, and procurement Research Project: Muscle Regeneration & Ulcers • Investigated the interplay between muscle regeneration, iron, and oxidative stress in pressure ulcers, utilizing mouse models and deploying confocal microscopy.
• Administered subcutaneous drug injections in mice and monitored their responses to pressure-induced injuries, employing magnet applications.
• Conducted euthanasia, tissue harvesting, and necropsies of mice muscles while ensuring ethical and procedural compliance.
• Performed genotyping and DNA extraction from mice ear samples, contributing to the comprehensive data set for analysis.
• Analysed confocal images of immunofluorescence (IF) stained mice skin/muscle tissues, extracting insightful data regarding cellular and tissue responses. Research Project: Investigation into Clonal Expansion Dynamics in Cancer Cells
• Explored the speed and dynamics of clonal expansion in mixed cultures of cancer cells, investigating the impact of anti-cancer drug combinations through simplified in vitro models of cancer evolution.
• Established growth curves and IC50 for Imatinib treatment in wild-type and mutant Ba/F3 cell lines, utilising the CCK-8 proliferation assay to deduce cellular responses and drug efficacy.
Singapore General HospitalResearch Officer I
Jul. 2017 - Nov. 2020Associate Professor Charles Chuah Laboratory for Leukemia Therapeutic Strategies • Trained medical officers/university attachment students on laboratory techniques, operational procedures, and laboratory equipment for their research projects. • Trained end-users on basic operational procedures and laboratory equipment. • Responsible for the procurement reagents and equipment, managing the safety of the laboratory. • Awarded $100,000 ONCO-ACP Collaborative Scheme 2015 for preliminary in vitro experiments to treat blast phase chronic myeloid leukemia (BP-CML) using mefloquine. • Led NUS Office-Safety Health and Environmental (OSHE) resulting in recommendation for Continuation of Certification. • Investigated in vitro effects and mechanism of action (MOA) of phenolic compound extracted from a medicinal plant on BP-CML:
o Collaborative project with A/Prof. Koh Hwee Ling (Department of Pharmacy, NUS) and Dr Fan Hao (a computational biologist, A*STAR-Bioinformatics Institute). • Investigated the in vitro effects and MOA of anti-malaria drug, mefloquine, on BP-CML.
• Identified the BIM deletion polymorphism in Imatinib-treated Asian CML patients.
Duke-NUS Medical SchoolResearch Assistant
Jul. 2016 - Jun. 2017SingaporeAssociate Professor Charles Chuah's Research Lab Laboratory for Leukaemia Therapeutic Strategies (see details above)
Singapore General HospitalResearch Officer II
Mar. 2014 - Aug. 2016Associate Professor Charles Chuah's Research Lab Laboratory for Leukaemia Therapeutic Strategies (See details above)
Church of Risen ChristPastoral Youth Coordinator
Nov. 2011 - Mar. 2014Toa Payoh Central, Singapore• Formed a youth group & young working adult group.
• Provided guidance, mentoring and direction to the youth & young working adult groups. • Managed youth’s budgets/finances for the youth groups.
• Organize fund raising events to raise funds for the youth events.
A*STAR - Agency for Science, Technology and ResearchLaboratory Officer
Jan. 2007 - Feb. 2011SingaporeProfessor Li Jun's Research Lab
Supramolecular Biomaterials Laboratory
National University of Singapore, Chemistry DepartmentLaboratory Officer
Jan. 2005 - Dec. 2007Associate Professor Suresh Valiyaveettil's Lab
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