Prof of public health dentistry@Sapienza Università di Roma
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I am a dentist working in academia. My expertise is public health and prevention, cost analysis of healthMore...
Bachisio Ziccheddu
Computational Biologist@University of Miami - Sylvester Comprehensive Cancer Center
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I am a passionate and dedicated computational biologist specializing in hematological cancers, with a focus on leveraging genomic data to understand disease mechanisms and resistance to therapies. My career began in molecular biology during internships in Italy. However, my interests soon shifted to computational biology, driven by a growing fascination with genomics and bioinformatics.
With a master's degree in genomic statistics and extensive experience working with leading research institutions such as the IRCCS Istituto Nazionale dei Tumori, University of Turin and the Sylvester Comprehensive Cancer Center at the University of Miami, I have honed my expertise in analyzing large-scale genomic datasets. My work spans multiple myeloma and lymphoma, where I focus on resistance mechanisms to advanced therapies, including CAR-T cell therapy and monoclonal antibodies.
My research integrates whole genome sequencing (WGS), RNA-sequencing, single-cell transcriptomics, and flow cytometry to explore the intricate relationship between tumor biology and the immune system. These efforts have led to novel insights into disease progression, personalized medicine, and the development of machine learning models for clinical outcome predictions.More...