Yale UniversityPostdoc/ Research associate
Jan. 1999 - Dec. 2003During my PhD in Experimental Pharmacology (1996 to 1999) I have studied the role of the transcription factor NF-kB in different models of acute and chronic inflammation demonstrating that inhibitors of NF-kB activation display a remarkable in vivo anti-inflammatory activity. I have directed the efforts on this research path even further after beginning a post-doctoral training in the laboratory of Prof. Sankar Ghosh, at Yale University (1999), where I have investigated novel approaches to successfully target the NF-kB pathway and that can be used as anti-inflammatory therapy. During this time (from 1999-2003) I have expanded my knowledge on inflammation by focusing on immune-mediated inflammatory diseases and investigated signalling pathways by which the T cell receptor activates NF-kB in T cells.